!IV.4. Constant pressure ensemble run !This input runs MC simulation in the isothermal-isobaric ensemble. The !solute is the protein a Na+ - DMP- ion pair. FILE nadmp TITL run 2 slt molecs in water, only moves TITL NA+DMP-: KOLLMAN-STRAATSMA(NA+) HRDW VC32 ! 32-bit vector SVVC SPCC 7.75 ! Solvent cutoff SUVC MIGC 0.0 ! MI on the solute PBCN RECT 32.031 21.354 21.354 TEMP 298 NSLV 484 STEP 0.10 00.0 0.55 40.0 05 SVPT TIP3 TIP3 SUPT AM94 SAMP FBSC 0.5 ! Scaled force-biased sampling 2 4.00 0.2 7.0 1.0 PMOD AM94 1 ! Potential library modification 49 46 11 1.59955E+00 0.478833E-01 SLTA SMPL MMC READ 8 49 2.70000 0.0 0.00000 1.00000 1 38 0.0 0.0 0.0 0.91200 4 35 0.74000 0.0 1.28171 -0.65500 4 35 0.74000 0.0 -1.28171 -0.65500 4 37 -0.99164 -1.25560 0.00000 -0.41000 4 37 -0.99164 1.25560 0.00000 -0.41000 4 4 -1.92075 1.43300 1.07251 0.10900 4 4 -1.92075 -1.43300 -1.07251 0.10900 4 IBEN UNIF ISOT 1.0 250.0 500 100 !(TPN) ensemble CNFG READ ASCI RUNS 2000000 50000 1000000 0100000 100000 STOP SLFT !Files needed for run: ! * nadmp.crd: initial configuration. !Files created by the run: ! * nadmp.ckp: checkpoint file after the run; ! * nadmp.crd: initial configuration. ! * nadmp.2.crd: final configuration after the run.